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Study protocol for statin web-based investigation of side effects (StatinWISE): a series of randomised controlled N-of-1 trials comparing atorvastatin and placebo in UK primary care
INTRODUCTION: Statins are effective at preventing cardiovascular disease, widely prescribed and their use is growing. Uncertainty persists about whether they cause symptomatic muscle adverse effects, such as pain and weakness, in the absence of statin myopathy. Discrepancies between data from observ...
Autores principales: | Herrett, Emily, Williamson, Elizabeth, Beaumont, Danielle, Prowse, Danielle, Youssouf, Nabila, Brack, Kieran, Armitage, Jane, Goldacre, Ben, MacDonald, Thomas, van Staa, Tjeerd, Roberts, Ian, Shakur-Still, Haleema, Smeeth, Liam |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BMJ Publishing Group
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5719321/ https://www.ncbi.nlm.nih.gov/pubmed/29197834 http://dx.doi.org/10.1136/bmjopen-2017-016604 |
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