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Transplantation of a quaternary structure neutralizing antibody epitope from dengue virus serotype 3 into serotype 4

Dengue vaccine trials have revealed deficits in our understanding of the mechanisms of protective immunity, demonstrating a need to measure epitope-specific antibody responses against each DENV serotype. HmAb 5J7 binds to a complex, 3-monomer spanning quaternary epitope in the DENV3 envelope (E) pro...

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Detalles Bibliográficos
Autores principales:	Widman, Douglas G., Young, Ellen, Nivarthi, Usha, Swanstrom, Jesica A., Royal, Scott R., Yount, Boyd L., Debbink, Kari, Begley, Matthew, Marcet, Stephanie, Durbin, Anna, de Silva, Aravinda M., Messer, William B., Baric, Ralph S.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2017
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5719398/ https://www.ncbi.nlm.nih.gov/pubmed/29215033 http://dx.doi.org/10.1038/s41598-017-17355-5

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