The role of Cdx2 as a lineage specific transcriptional repressor for pluripotent network during the first developmental cell lineage segregation

The first cellular differentiation event in mouse development leads to the formation of the blastocyst consisting of the inner cell mass (ICM) and trophectoderm (TE). The transcription factor CDX2 is required for proper TE specification, where it promotes expression of TE genes, and represses expres...

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Detalles Bibliográficos
Autores principales: Huang, Daosheng, Guo, Guoji, Yuan, Ping, Ralston, Amy, Sun, Lingang, Huss, Mikael, Mistri, Tapan, Pinello, Luca, Ng, Huck Hui, Yuan, Guocheng, Ji, Junfeng, Rossant, Janet, Robson, Paul, Han, Xiaoping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5719399/
https://www.ncbi.nlm.nih.gov/pubmed/29214996
http://dx.doi.org/10.1038/s41598-017-16009-w

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