Engineering an aldehyde dehydrogenase toward its substrates, 3-hydroxypropanal and NAD(+), for enhancing the production of 3-hydroxypropionic acid

3-Hydroxypropionic acid (3-HP) can be produced via the biological route involving two enzymatic reactions: dehydration of glycerol to 3-hydroxypropanal (3-HPA) and then oxidation to 3-HP. However, commercial production of 3-HP using recombinant microorganisms has been hampered with several problems,...

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Detalles Bibliográficos
Autores principales: Park, Ye Seop, Choi, Un Jong, Nam, Nguyen Hoai, Choi, Sang Jin, Nasir, Abdul, Lee, Sun-Gu, Kim, Kyung Jin, Jung, Gyoo Yeol, Choi, Sangdun, Shim, Jeung Yeop, Park, Sunghoon, Yoo, Tae Hyeon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5719400/
https://www.ncbi.nlm.nih.gov/pubmed/29214999
http://dx.doi.org/10.1038/s41598-017-15400-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5719400/
https://www.ncbi.nlm.nih.gov/pubmed/29214999
http://dx.doi.org/10.1038/s41598-017-15400-x

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