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Multivalent cross-linking of actin filaments and microtubules through the microtubule-associated protein Tau
Microtubule-associated proteins regulate microtubule dynamics, bundle actin filaments, and cross-link actin filaments with microtubules. In addition, aberrant interaction of the microtubule-associated protein Tau with filamentous actin is connected to synaptic impairment in Alzheimer’s disease. Here...
Autores principales: | Cabrales Fontela, Yunior, Kadavath, Harindranath, Biernat, Jacek, Riedel, Dietmar, Mandelkow, Eckhard, Zweckstetter, Markus |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5719408/ https://www.ncbi.nlm.nih.gov/pubmed/29215007 http://dx.doi.org/10.1038/s41467-017-02230-8 |
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