Cargando…

Local Production of Activated Factor X in Atherosclerotic Plaque Induced Vascular Smooth Muscle Cell Senescence

Our previous study demonstrated that coagulation factor Xa (FXa) induced endothelial cell senescence, resulting in inflammation and impaired angiogenesis. This mechanism is dictated through protease-activated receptors, PARs, insulin-like growth factor-binding protein 5 (IGFBP-5), and p53. Activatio...

Descripción completa

Detalles Bibliográficos
Autores principales:	Sanada, Fumihiro, Muratsu, Jun, Otsu, Rei, Shimizu, Hideo, Koibuchi, Nobutaka, Uchida, Kazutaka, Taniyama, Yoshiaki, Yoshimura, Shinichi, Rakugi, Hiromi, Morishita, Ryuichi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2017
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5719421/ https://www.ncbi.nlm.nih.gov/pubmed/29215061 http://dx.doi.org/10.1038/s41598-017-17508-6

Ejemplares similares

IGF Binding Protein-5 Induces Cell Senescence
por: Sanada, Fumihiro, et al.
Publicado: (2018)

Source of Chronic Inflammation in Aging
por: Sanada, Fumihiro, et al.
Publicado: (2018)

Gene-Therapeutic Strategies Targeting Angiogenesis in Peripheral Artery Disease
por: Sanada, Fumihiro, et al.
Publicado: (2018)

Activated Factor X Induces Endothelial Cell Senescence Through IGFBP-5
por: Sanada, Fumihiro, et al.
Publicado: (2016)

Hepatocyte Growth Factor Prevented High-Fat Diet-Induced Obesity and Improved Insulin Resistance in Mice
por: Muratsu, Jun, et al.
Publicado: (2017)

Blocking Periostin Prevented Development of Inflammation in Rhabdomyolysis-Induced Acute Kidney Injury Mice Model
por: Muratsu, Jun, et al.
Publicado: (2022)

Periostin Short Fragment with Exon 17 via Aberrant Alternative Splicing Is Required for Breast Cancer Growth and Metastasis
por: Ikeda-Iwabu, Yuka, et al.
Publicado: (2021)

Therapeutic Angiogenesis Using HGF Plasmid
por: Sanada, Fumihiro, et al.
Publicado: (2020)

Periostin Exon-21 Antibody Neutralization of Triple-Negative Breast Cancer Cell-Derived Periostin Regulates Tumor-Associated Macrophage Polarization and Angiogenesis
por: Fujikawa, Tatsuya, et al.
Publicado: (2021)

Therapeutic Angiogenesis by Gene Therapy for Critical Limb Ischemia: Choice of Biological Agent
por: Sanada, Fumihiro, et al.
Publicado: (2014)

Cardiac and Renal Protective Effects of Irbesartan via Peroxisome Proliferator‐Activated Receptorγ–Hepatocyte Growth Factor Pathway Independent of Angiotensin II Type 1a Receptor Blockade in Mouse Model of Salt‐Sensitive Hypertension
por: Kusunoki, Hiroshi, et al.
Publicado: (2013)

Periostin blockade overcomes chemoresistance via restricting the expansion of mesenchymal tumor subpopulations in breast cancer
por: Nakazawa, Youya, et al.
Publicado: (2018)

Lower body mass index potentiates the association between skipping breakfast and prevalence of proteinuria
por: Muratsu, Jun, et al.
Publicado: (2022)

The Combination of High Levels of Adiponectin and Insulin Resistance Are Affected by Aging in Non-Obese Old Peoples
por: Muratsu, Jun, et al.
Publicado: (2022)

Effects of Serum Lipid Smoothness on the Progression and Vulnerability of Atherosclerotic Plaques in Rabbits
por: Zou, Xiao, et al.
Publicado: (2014)

Insight into the Role of Angiopoietins in Ageing-Associated Diseases
por: Hayashi, Shin-ichiro, et al.
Publicado: (2020)

TRAIL-expressing T cells induce apoptosis of vascular smooth muscle cells in the atherosclerotic plaque
por: Sato, Kayoko, et al.
Publicado: (2006)

An update on clonality: what smooth muscle cell type makes up the atherosclerotic plaque?
por: Schwartz, Stephen M., et al.
Publicado: (2018)

Angiogenesis in the atherosclerotic plaque
por: Camaré, Caroline, et al.
Publicado: (2017)

Integrin beta3 regulates clonality and fate of smooth muscle-derived atherosclerotic plaque cells
por: Misra, Ashish, et al.
Publicado: (2018)

Smooth muscle-derived macrophage-like cells contribute to multiple cell lineages in the atherosclerotic plaque
por: Li, Yi, et al.
Publicado: (2021)

Immature Vascular Smooth Muscle Cells in Healthy Murine Arteries and Atherosclerotic Plaques: Localization and Activity
por: Balatskiy, Alexander, et al.
Publicado: (2022)

Neutralization of S100A4 induces stabilization of atherosclerotic plaques: role of smooth muscle cells
por: Sakic, Antonija, et al.
Publicado: (2020)

Female gene networks are expressed in myofibroblast-like smooth muscle cells in vulnerable atherosclerotic plaques
por: Benavente, Ernest Diez, et al.
Publicado: (2023)

Female Gene Networks Are Expressed in Myofibroblast-Like Smooth Muscle Cells in Vulnerable Atherosclerotic Plaques
por: Diez Benavente, Ernest, et al.
Publicado: (2023)

A Patient with Carotid Mobile Plaques Treated by Carotid Artery Stenting Using a Double-layer Micromesh Stent
por: Kuwahara, Shuntaro, et al.
Publicado: (2020)

Therapeutic vaccine for chronic diseases after the COVID-19 Era
por: Nakagami, Hironori, et al.
Publicado: (2021)

Profilin-1 Is Expressed in Human Atherosclerotic Plaques and Induces Atherogenic Effects on Vascular Smooth Muscle Cells
por: Caglayan, Evren, et al.
Publicado: (2010)

Nox4 NADPH oxidase contributes to smooth muscle cell phenotypes associated with unstable atherosclerotic plaques
por: Xu, Shaoping, et al.
Publicado: (2014)

Distribution of Matrix Metalloproteinases in Human Atherosclerotic Carotid Plaques and Their Production by Smooth Muscle Cells and Macrophage Subsets
por: Jager, Nynke A., et al.
Publicado: (2015)

[(18)F]FDG Uptake in the Aortic Wall Smooth Muscle of Atherosclerotic Plaques in the Simian Atherosclerosis Model
por: Iwaki, Takayuki, et al.
Publicado: (2016)

Smad3 regulates smooth muscle cell fate and mediates adverse remodeling and calcification of the atherosclerotic plaque
por: Cheng, Paul, et al.
Publicado: (2022)

Imaging the carotid atherosclerotic plaque
por: Neumann, Sandra, et al.
Publicado: (2019)

Atherosclerotic Plaque Biomarkers: Beyond the Horizon of the Vulnerable Plaque
por: W. van Lammeren, Guus, et al.
Publicado: (2011)

Recent Advances in Fluorescent Angioscopy for Molecular Imaging of Human Atherosclerotic Coronary Plaque
por: Uchida, Yasumi
Publicado: (2017)

Myeloperoxidase-oxidized high density lipoprotein impairs atherosclerotic plaque stability by inhibiting smooth muscle cell migration
por: Zhou, Boda, et al.
Publicado: (2017)

Impact of Alirocumab on Release Markers of Atherosclerotic Plaque Vulnerability in Patients with Mixed Hyperlipidemia and Vulnerable Atherosclerotic Plaque
por: Kosowski, Michał, et al.
Publicado: (2022)

Osteopontin and osteoprotegerin in atherosclerotic plaque – are they significant markers of plaque vulnerability?
por: Strobescu-Ciobanu, Cristina, et al.
Publicado: (2020)

The Elusive Origin of Atherosclerotic Plaque Calcification
por: Canet-Soulas, Emmanuelle, et al.
Publicado: (2021)

Clinical Molecular Imaging for Atherosclerotic Plaque
por: Kondakov, Anton, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_r6caaprndq7e9gjc3f8el6c382