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Structural insights into the potency of SK channel positive modulators

Small-conductance Ca(2+)-activated K(+) (SK) channels play essential roles in the regulation of cellular excitability and have been implicated in neurological and cardiovascular diseases through both animal model studies and human genetic association studies. Over the past two decades, positive modu...

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Detalles Bibliográficos
Autores principales: Nam, Young-Woo, Orfali, Razan, Liu, Tingting, Yu, Kunqian, Cui, Meng, Wulff, Heike, Zhang, Miao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5719431/
https://www.ncbi.nlm.nih.gov/pubmed/29214998
http://dx.doi.org/10.1038/s41598-017-16607-8

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