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Structural insights into the potency of SK channel positive modulators
Small-conductance Ca(2+)-activated K(+) (SK) channels play essential roles in the regulation of cellular excitability and have been implicated in neurological and cardiovascular diseases through both animal model studies and human genetic association studies. Over the past two decades, positive modu...
Autores principales: | Nam, Young-Woo, Orfali, Razan, Liu, Tingting, Yu, Kunqian, Cui, Meng, Wulff, Heike, Zhang, Miao |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5719431/ https://www.ncbi.nlm.nih.gov/pubmed/29214998 http://dx.doi.org/10.1038/s41598-017-16607-8 |
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