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Endomucin inhibits VEGF-induced endothelial cell migration, growth, and morphogenesis by modulating VEGFR2 signaling
Angiogenesis is central to both normal and pathologic processes. Endothelial cells (ECs) express O-glycoproteins that are believed to play important roles in vascular development and stability. Endomucin-1 (EMCN) is a type I O-glycosylated, sialic-rich glycoprotein, specifically expressed by venous...
Autores principales: | Park-Windhol, Cindy, Ng, Yin Shan, Yang, Jinling, Primo, Vincent, Saint-Geniez, Magali, D’Amore, Patricia A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5719432/ https://www.ncbi.nlm.nih.gov/pubmed/29215001 http://dx.doi.org/10.1038/s41598-017-16852-x |
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