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Active-site plasticity revealed in the asymmetric dimer of AnPrx6 the 1-Cys peroxiredoxin and molecular chaperone from Anabaena sp. PCC 7120
Peroxiredoxins (Prxs) are vital regulators of intracellular reactive oxygen species levels in all living organisms. Their activity depends on one or two catalytically active cysteine residues, the peroxidatic Cys (C(P)) and, if present, the resolving Cys (C(R)). A detailed catalytic cycle has been d...
Autores principales: | Mishra, Yogesh, Hall, Michael, Locmelis, Roland, Nam, Kwangho, Söderberg, Christopher A. G., Storm, Patrik, Chaurasia, Neha, Rai, Lal Chand, Jansson, Stefan, Schröder, Wolfgang P., Sauer, Uwe H. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5719442/ https://www.ncbi.nlm.nih.gov/pubmed/29215017 http://dx.doi.org/10.1038/s41598-017-17044-3 |
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