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The evolution of the macrophage-specific enhancer (Fms intronic regulatory element) within the CSF1R locus of vertebrates
The Csf1r locus encodes the receptor for macrophage colony-stimulating factor, which controls the proliferation, differentiation and survival of macrophages. The 300 bp Fms intronic regulatory element (FIRE), within the second intron of Csf1r, is necessary and sufficient to direct macrophage-specifi...
Autores principales: | Hume, David A., Wollscheid-Lengeling, Evi, Rojo, Rocio, Pridans, Clare |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5719456/ https://www.ncbi.nlm.nih.gov/pubmed/29215000 http://dx.doi.org/10.1038/s41598-017-15999-x |
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