Generation of stable PDX derived cell lines using conditional reprogramming

Efforts to develop effective cancer therapeutics have been hindered by a lack of clinically predictive preclinical models which recapitulate this complex disease. Patient derived xenograft (PDX) models have emerged as valuable tools for translational research but have several practical limitations i...

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Detalles Bibliográficos
Autores principales: Borodovsky, Alexandra, McQuiston, Travis J., Stetson, Daniel, Ahmed, Ambar, Whitston, David, Zhang, Jingwen, Grondine, Michael, Lawson, Deborah, Challberg, Sharon S., Zinda, Michael, Pollok, Brian A., Dougherty, Brian A., D’Cruz, Celina M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Letter to the Editor
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5719579/
https://www.ncbi.nlm.nih.gov/pubmed/29212548
http://dx.doi.org/10.1186/s12943-017-0745-1

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