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Comparison of a 3D multi‐group [Formula: see text] particle transport code with Monte Carlo for intercavitary brachytherapy of the cervix uteri

A patient dose distribution was calculated by a 3D multi‐group [Formula: see text] particle transport code for intracavitary brachytherapy of the cervix uteri and compared to previously published Monte Carlo results. A Cs‐137 LDR intracavitary brachytherapy CT data set was chosen from our clinical d...

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Autores principales: Gifford, Kent A., Wareing, Todd A., Failla, Gregory, Horton, John L., Eifel, Patricia J., Mourtada, Firas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5719779/
https://www.ncbi.nlm.nih.gov/pubmed/20160682
http://dx.doi.org/10.1120/jacmp.v11i1.3103
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author Gifford, Kent A.
Wareing, Todd A.
Failla, Gregory
Horton, John L.
Eifel, Patricia J.
Mourtada, Firas
author_facet Gifford, Kent A.
Wareing, Todd A.
Failla, Gregory
Horton, John L.
Eifel, Patricia J.
Mourtada, Firas
author_sort Gifford, Kent A.
collection PubMed
description A patient dose distribution was calculated by a 3D multi‐group [Formula: see text] particle transport code for intracavitary brachytherapy of the cervix uteri and compared to previously published Monte Carlo results. A Cs‐137 LDR intracavitary brachytherapy CT data set was chosen from our clinical database. MCNPX version 2.5.c, was used to calculate the dose distribution. A 3D multi‐group [Formula: see text] particle transport code, Attila version 6.1.1 was used to simulate the same patient. Each patient applicator was built in SolidWorks, a mechanical design package, and then assembled with a coordinate transformation and rotation for the patient. The SolidWorks exported applicator geometry was imported into Attila for calculation. Dose matrices were overlaid on the patient CT data set. Dose volume histograms and point doses were compared. The MCNPX calculation required 14.8 hours, whereas the Attila calculation required 22.2 minutes on a 1.8 GHz AMD Opteron CPU. Agreement between Attila and MCNPX dose calculations at the ICRU 38 points was within [Formula: see text]. Calculated doses to the 2 cc and 5 cc volumes of highest dose differed by not more than [Formula: see text] between the two codes. Dose and DVH overlays agreed well qualitatively. Attila can calculate dose accurately and efficiently for this Cs‐137 CT‐based patient geometry. Our data showed that a three‐group cross‐section set is adequate for Cs‐137 computations. Future work is aimed at implementing an optimized version of Attila for radiotherapy calculations. PACS number: 87.53.Jw
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spelling pubmed-57197792018-04-02 Comparison of a 3D multi‐group [Formula: see text] particle transport code with Monte Carlo for intercavitary brachytherapy of the cervix uteri Gifford, Kent A. Wareing, Todd A. Failla, Gregory Horton, John L. Eifel, Patricia J. Mourtada, Firas J Appl Clin Med Phys Radiation Oncology Physics A patient dose distribution was calculated by a 3D multi‐group [Formula: see text] particle transport code for intracavitary brachytherapy of the cervix uteri and compared to previously published Monte Carlo results. A Cs‐137 LDR intracavitary brachytherapy CT data set was chosen from our clinical database. MCNPX version 2.5.c, was used to calculate the dose distribution. A 3D multi‐group [Formula: see text] particle transport code, Attila version 6.1.1 was used to simulate the same patient. Each patient applicator was built in SolidWorks, a mechanical design package, and then assembled with a coordinate transformation and rotation for the patient. The SolidWorks exported applicator geometry was imported into Attila for calculation. Dose matrices were overlaid on the patient CT data set. Dose volume histograms and point doses were compared. The MCNPX calculation required 14.8 hours, whereas the Attila calculation required 22.2 minutes on a 1.8 GHz AMD Opteron CPU. Agreement between Attila and MCNPX dose calculations at the ICRU 38 points was within [Formula: see text]. Calculated doses to the 2 cc and 5 cc volumes of highest dose differed by not more than [Formula: see text] between the two codes. Dose and DVH overlays agreed well qualitatively. Attila can calculate dose accurately and efficiently for this Cs‐137 CT‐based patient geometry. Our data showed that a three‐group cross‐section set is adequate for Cs‐137 computations. Future work is aimed at implementing an optimized version of Attila for radiotherapy calculations. PACS number: 87.53.Jw John Wiley and Sons Inc. 2009-12-03 /pmc/articles/PMC5719779/ /pubmed/20160682 http://dx.doi.org/10.1120/jacmp.v11i1.3103 Text en © 2010 The Authors. This is an open access article under the terms of the Creative Commons Attribution (http://creativecommons.org/licenses/by/3.0/) License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.
spellingShingle Radiation Oncology Physics
Gifford, Kent A.
Wareing, Todd A.
Failla, Gregory
Horton, John L.
Eifel, Patricia J.
Mourtada, Firas
Comparison of a 3D multi‐group [Formula: see text] particle transport code with Monte Carlo for intercavitary brachytherapy of the cervix uteri
title Comparison of a 3D multi‐group [Formula: see text] particle transport code with Monte Carlo for intercavitary brachytherapy of the cervix uteri
title_full Comparison of a 3D multi‐group [Formula: see text] particle transport code with Monte Carlo for intercavitary brachytherapy of the cervix uteri
title_fullStr Comparison of a 3D multi‐group [Formula: see text] particle transport code with Monte Carlo for intercavitary brachytherapy of the cervix uteri
title_full_unstemmed Comparison of a 3D multi‐group [Formula: see text] particle transport code with Monte Carlo for intercavitary brachytherapy of the cervix uteri
title_short Comparison of a 3D multi‐group [Formula: see text] particle transport code with Monte Carlo for intercavitary brachytherapy of the cervix uteri
title_sort comparison of a 3d multi‐group [formula: see text] particle transport code with monte carlo for intercavitary brachytherapy of the cervix uteri
topic Radiation Oncology Physics
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5719779/
https://www.ncbi.nlm.nih.gov/pubmed/20160682
http://dx.doi.org/10.1120/jacmp.v11i1.3103
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