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Target and peripheral dose during patient repositioning with the Gamma Knife automatic positioning system (APS) device

The GammaPlan treatment planning system does not account for the leakage and scatter dose during APS repositioning. In this study, the dose delivered to the target site and its periphery from the defocus stage and intershot couch transit (couch motion from the focus to defocus position and back) ass...

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Autores principales: Tran, Tuan‐Anh, Stanley, Thomas, Malhotra, Harish K., deBoer, Steven F., Prasad, Dheerendra, Podgorsak, Matthew B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5719780/
https://www.ncbi.nlm.nih.gov/pubmed/20160701
http://dx.doi.org/10.1120/jacmp.v11i1.3150
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author Tran, Tuan‐Anh
Stanley, Thomas
Malhotra, Harish K.
deBoer, Steven F.
Prasad, Dheerendra
Podgorsak, Matthew B.
author_facet Tran, Tuan‐Anh
Stanley, Thomas
Malhotra, Harish K.
deBoer, Steven F.
Prasad, Dheerendra
Podgorsak, Matthew B.
author_sort Tran, Tuan‐Anh
collection PubMed
description The GammaPlan treatment planning system does not account for the leakage and scatter dose during APS repositioning. In this study, the dose delivered to the target site and its periphery from the defocus stage and intershot couch transit (couch motion from the focus to defocus position and back) associated with APS repositioning are measured for the Gamma Knife model 4C. A stereotactic head‐frame was attached to a Leksell 16 cm diameter spherical phantom with a calibrated ion chamber at its center. Using a fiducial box, CT images of the phantom were acquired and registered in the GammaPlan treatment planning system to determine the coordinates of the target (center of the phantom). An absorbed dose of 10 Gy to the 50% isodose line was prescribed to the target site for all measurements. Plans were generated for the 8, 14 and 18 mm collimator helmets to determine the relationship of measured dose to the number of repositions of the APS system and to the helmet size. The target coordinate was identical throughout entire study and there was no movement of the APS between various shots. This allowed for measurement of intershot transit dose at the target site and its periphery. The couch was paused in the defocus position, allowing defocus dose measurements at the intracranial target and periphery. Measured dose increases with frequency of repositioning and with helmet collimator size. During couch transit, the target receives more dose than peripheral regions; however, in the defocus position, the greatest dose is superior to the target site. The automatic positioning system for the Leksell Gamma Knife model 4C results in an additional dose of up to [Formula: see text] , and [Formula: see text] to the target site; its periphery receives additional dose that varies depending on its position relative to the target. There is also dose contribution to the patient in the defocus position, where the APS repositions the patient from one treatment coordinate to another. This may be important for treatment areas around critical structures within the brain. Further characterization of the defocus and transit exposures and development of a dose calculation algorithm to account for these doses would improve the accuracy of the delivered plan. PACS numbers: 87.53.‐j, 87.53.Bn, 87.53.Dq, 87.53.Ly
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spelling pubmed-57197802018-04-02 Target and peripheral dose during patient repositioning with the Gamma Knife automatic positioning system (APS) device Tran, Tuan‐Anh Stanley, Thomas Malhotra, Harish K. deBoer, Steven F. Prasad, Dheerendra Podgorsak, Matthew B. J Appl Clin Med Phys Radiation Oncology Physics The GammaPlan treatment planning system does not account for the leakage and scatter dose during APS repositioning. In this study, the dose delivered to the target site and its periphery from the defocus stage and intershot couch transit (couch motion from the focus to defocus position and back) associated with APS repositioning are measured for the Gamma Knife model 4C. A stereotactic head‐frame was attached to a Leksell 16 cm diameter spherical phantom with a calibrated ion chamber at its center. Using a fiducial box, CT images of the phantom were acquired and registered in the GammaPlan treatment planning system to determine the coordinates of the target (center of the phantom). An absorbed dose of 10 Gy to the 50% isodose line was prescribed to the target site for all measurements. Plans were generated for the 8, 14 and 18 mm collimator helmets to determine the relationship of measured dose to the number of repositions of the APS system and to the helmet size. The target coordinate was identical throughout entire study and there was no movement of the APS between various shots. This allowed for measurement of intershot transit dose at the target site and its periphery. The couch was paused in the defocus position, allowing defocus dose measurements at the intracranial target and periphery. Measured dose increases with frequency of repositioning and with helmet collimator size. During couch transit, the target receives more dose than peripheral regions; however, in the defocus position, the greatest dose is superior to the target site. The automatic positioning system for the Leksell Gamma Knife model 4C results in an additional dose of up to [Formula: see text] , and [Formula: see text] to the target site; its periphery receives additional dose that varies depending on its position relative to the target. There is also dose contribution to the patient in the defocus position, where the APS repositions the patient from one treatment coordinate to another. This may be important for treatment areas around critical structures within the brain. Further characterization of the defocus and transit exposures and development of a dose calculation algorithm to account for these doses would improve the accuracy of the delivered plan. PACS numbers: 87.53.‐j, 87.53.Bn, 87.53.Dq, 87.53.Ly John Wiley and Sons Inc. 2010-01-28 /pmc/articles/PMC5719780/ /pubmed/20160701 http://dx.doi.org/10.1120/jacmp.v11i1.3150 Text en © 2010 The Authors. This is an open access article under the terms of the Creative Commons Attribution (http://creativecommons.org/licenses/by/3.0/) License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.
spellingShingle Radiation Oncology Physics
Tran, Tuan‐Anh
Stanley, Thomas
Malhotra, Harish K.
deBoer, Steven F.
Prasad, Dheerendra
Podgorsak, Matthew B.
Target and peripheral dose during patient repositioning with the Gamma Knife automatic positioning system (APS) device
title Target and peripheral dose during patient repositioning with the Gamma Knife automatic positioning system (APS) device
title_full Target and peripheral dose during patient repositioning with the Gamma Knife automatic positioning system (APS) device
title_fullStr Target and peripheral dose during patient repositioning with the Gamma Knife automatic positioning system (APS) device
title_full_unstemmed Target and peripheral dose during patient repositioning with the Gamma Knife automatic positioning system (APS) device
title_short Target and peripheral dose during patient repositioning with the Gamma Knife automatic positioning system (APS) device
title_sort target and peripheral dose during patient repositioning with the gamma knife automatic positioning system (aps) device
topic Radiation Oncology Physics
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5719780/
https://www.ncbi.nlm.nih.gov/pubmed/20160701
http://dx.doi.org/10.1120/jacmp.v11i1.3150
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