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Synergistic antitumor interaction between valproic acid, capecitabine and radiotherapy in colorectal cancer: critical role of p53
BACKGROUND: Recurrence with distant metastases has become the predominant pattern of failure in locally advanced rectal cancer (LARC), thus the integration of new antineoplastic agents into preoperative fluoropyrimidine-based chemo-radiotherapy represents a clinical challenge to implement an intensi...
Autores principales: | Terranova-Barberio, Manuela, Pecori, Biagio, Roca, Maria Serena, Imbimbo, Serena, Bruzzese, Francesca, Leone, Alessandra, Muto, Paolo, Delrio, Paolo, Avallone, Antonio, Budillon, Alfredo, Di Gennaro, Elena |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5719792/ https://www.ncbi.nlm.nih.gov/pubmed/29212503 http://dx.doi.org/10.1186/s13046-017-0647-5 |
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