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The intrahippocampal kainate mouse model of mesial temporal lobe epilepsy: Lack of electrographic seizure‐like events in sham controls

OBJECTIVE: There is an ongoing debate about definition of seizures in experimental models of acquired epilepsy and how important adequate sham controls are in this respect. For instance, several mouse and rat strains exhibit high‐voltage rhythmic spike or spike‐wave discharges in the cortical electr...

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Detalles Bibliográficos
Autores principales: Twele, Friederike, Schidlitzki, Alina, Töllner, Kathrin, Löscher, Wolfgang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5719860/
https://www.ncbi.nlm.nih.gov/pubmed/29588947
http://dx.doi.org/10.1002/epi4.12044