Establishing and characterizing patient-derived xenografts using pre-chemotherapy percutaneous biopsy and post-chemotherapy surgical samples from a prospective neoadjuvant breast cancer study

BACKGROUND: Patient-derived xenografts (PDXs) are increasingly used in cancer research as a tool to inform cancer biology and drug response. Most available breast cancer PDXs have been generated in the metastatic setting. However, in the setting of operable breast cancer, PDX models both sensitive a...

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Detalles Bibliográficos
Autores principales: Yu, Jia, Qin, Bo, Moyer, Ann M., Sinnwell, Jason P., Thompson, Kevin J., Copland, John A., Marlow, Laura A., Miller, James L., Yin, Ping, Gao, Bowen, Minter-Dykhouse, Katherine, Tang, Xiaojia, McLaughlin, Sarah A., Moreno-Aspitia, Alvaro, Schweitzer, Anthony, Lu, Yan, Hubbard, Jason, Northfelt, Donald W., Gray, Richard J., Hunt, Katie, Conners, Amy L., Suman, Vera J., Kalari, Krishna R., Ingle, James N., Lou, Zhenkun, Visscher, Daniel W., Weinshilboum, Richard, Boughey, Judy C., Goetz, Matthew P., Wang, Liewei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5719923/
https://www.ncbi.nlm.nih.gov/pubmed/29212525
http://dx.doi.org/10.1186/s13058-017-0920-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5719923/
https://www.ncbi.nlm.nih.gov/pubmed/29212525
http://dx.doi.org/10.1186/s13058-017-0920-8

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