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Chromosome structures: reduction of certain problems with unequal gene content and gene paralogs to integer linear programming

BACKGROUND: Chromosome structure is a very limited model of the genome including the information about its chromosomes such as their linear or circular organization, the order of genes on them, and the DNA strand encoding a gene. Gene lengths, nucleotide composition, and intergenic regions are ignor...

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Detalles Bibliográficos
Autores principales: Lyubetsky, Vassily, Gershgorin, Roman, Gorbunov, Konstantin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5719933/
https://www.ncbi.nlm.nih.gov/pubmed/29212445
http://dx.doi.org/10.1186/s12859-017-1944-x