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The Origins, Specificity, and Potential Biological Relevance of Human Anti-IgG Hinge Autoantibodies

Human anti-IgG hinge (HAH) autoantibodies constitute a class of immunoglobulins that recognize cryptic epitopes in the hinge region of antibodies exposed after proteolytic cleavage, but do not bind to the intact IgG counterpart. Detailed molecular characterizations of HAH autoantibodies suggest that...

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Detalles Bibliográficos
Autores principales: Brezski, Randall J., Knight, David M., Jordan, Robert E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: TheScientificWorldJOURNAL 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5720009/
https://www.ncbi.nlm.nih.gov/pubmed/21623461
http://dx.doi.org/10.1100/tsw.2011.107