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The Origins, Specificity, and Potential Biological Relevance of Human Anti-IgG Hinge Autoantibodies
Human anti-IgG hinge (HAH) autoantibodies constitute a class of immunoglobulins that recognize cryptic epitopes in the hinge region of antibodies exposed after proteolytic cleavage, but do not bind to the intact IgG counterpart. Detailed molecular characterizations of HAH autoantibodies suggest that...
Autores principales: | Brezski, Randall J., Knight, David M., Jordan, Robert E. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
TheScientificWorldJOURNAL
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5720009/ https://www.ncbi.nlm.nih.gov/pubmed/21623461 http://dx.doi.org/10.1100/tsw.2011.107 |
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