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pH-triggered surface charge-switchable polymer micelles for the co-delivery of paclitaxel/disulfiram and overcoming multidrug resistance in cancer

Multidrug resistance (MDR) remains a major challenge for providing effective chemotherapy for many cancer patients. To address this issue, we report an intelligent polymer-based drug co-delivery system which could enhance and accelerate cellular uptake and reverse MDR. The nanodrug delivery systems...

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Detalles Bibliográficos
Autores principales: Huo, Qiang, Zhu, Jianhua, Niu, Yimin, Shi, Huihui, Gong, Yaxiang, Li, Yang, Song, Huihui, Liu, Yang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5720040/
https://www.ncbi.nlm.nih.gov/pubmed/29270012
http://dx.doi.org/10.2147/IJN.S144452