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The Effects of Montelukast on Antioxidant Enzymes and Proinflammatory Cytokines on the Heart, Liver, Lungs, and Kidneys in a Rat Model of Cecal Ligation and Puncture–Induced Sepsis

We investigated the potential protective effects of montelukast (MLK) on cecal ligation and puncture (CLP)–induced tissue injury in vital organs — liver, heart, kidneys, and especially lungs — through inhibition of the proinflammatory cytokine response and the generation of reactive oxygen species (...

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Detalles Bibliográficos
Autores principales: Coskun, Ali Kagan, Yigiter, Murat, Oral, Akgun, Odabasoglu, Fehmi, Halici, Zekai, Mentes, Oner, Cadirci, Elif, Atalay, Fadime, Suleyman, Halis
Formato: Online Artículo Texto
Lenguaje:English
Publicado: TheScientificWorldJOURNAL 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5720075/
https://www.ncbi.nlm.nih.gov/pubmed/21789470
http://dx.doi.org/10.1100/tsw.2011.122