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Evaluation of a commercially‐available block for spatially fractionated radiation therapy

In this paper, we present the dosimetric characteristics of a commercially‐produced universal GRID block for spatially fractioned radiation therapy. The dosimetric properties of the GRID block were evaluated. Ionization chamber and film measurements using both Kodak EDR2 and Gafchromic EBT film were...

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Autores principales: Buckey, Courtney, Stathakis, Sotirios, Cashon, Ken, Gutierrez, Alonso, Esquivel, Carlos, Shi, Chengyu, Papanikolaou, Nikos
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5720442/
https://www.ncbi.nlm.nih.gov/pubmed/20717082
http://dx.doi.org/10.1120/jacmp.v11i3.3163
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author Buckey, Courtney
Stathakis, Sotirios
Cashon, Ken
Gutierrez, Alonso
Esquivel, Carlos
Shi, Chengyu
Papanikolaou, Nikos
author_facet Buckey, Courtney
Stathakis, Sotirios
Cashon, Ken
Gutierrez, Alonso
Esquivel, Carlos
Shi, Chengyu
Papanikolaou, Nikos
author_sort Buckey, Courtney
collection PubMed
description In this paper, we present the dosimetric characteristics of a commercially‐produced universal GRID block for spatially fractioned radiation therapy. The dosimetric properties of the GRID block were evaluated. Ionization chamber and film measurements using both Kodak EDR2 and Gafchromic EBT film were performed in a solid water phantom to determine the relative output of the GRID block as well as its spatial dosimetric characteristics. The surface dose under the block and at the openings was measured using ultra thin TLDs. After introducing the GRID block into the treatment planning system, a treatment plan was created using the GRID block and also by creating a GRID pattern using the multi‐leaf collimator. The percent depth doses measured with film showed that there is a shift of the [Formula: see text] towards shallower depths for both energies (6 MV and 18 MV) under investigation. It was observed that the skin dose at the GRID openings was higher than the corresponding open field by a factor as high as 50% for both photon energies. The profiles showed the transmission under the block was in the order of 15–20% for 6 MV and 30% for 18 MV. The MUs calculated for a real patient using the block were about 80% less than the corresponding MUs for the same plan using the multileaf collimator to define the GRID. Based on this investigation, this brass GRID compensator is a viable alternative to other solid compensators or MLC‐based fields currently in use. Its ease of creation and use give it decided advantages. Its ability to be created once and used for multiple patients (by varying the collimation of the linear accelerator jaws) makes it attractive from a cost perspective. We believe this compensator can be put to clinical use, and will allow more centers to offer GRID therapy to their patients. PACS number: 87.53.Mr
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spelling pubmed-57204422018-04-02 Evaluation of a commercially‐available block for spatially fractionated radiation therapy Buckey, Courtney Stathakis, Sotirios Cashon, Ken Gutierrez, Alonso Esquivel, Carlos Shi, Chengyu Papanikolaou, Nikos J Appl Clin Med Phys Radiation Oncology Physics In this paper, we present the dosimetric characteristics of a commercially‐produced universal GRID block for spatially fractioned radiation therapy. The dosimetric properties of the GRID block were evaluated. Ionization chamber and film measurements using both Kodak EDR2 and Gafchromic EBT film were performed in a solid water phantom to determine the relative output of the GRID block as well as its spatial dosimetric characteristics. The surface dose under the block and at the openings was measured using ultra thin TLDs. After introducing the GRID block into the treatment planning system, a treatment plan was created using the GRID block and also by creating a GRID pattern using the multi‐leaf collimator. The percent depth doses measured with film showed that there is a shift of the [Formula: see text] towards shallower depths for both energies (6 MV and 18 MV) under investigation. It was observed that the skin dose at the GRID openings was higher than the corresponding open field by a factor as high as 50% for both photon energies. The profiles showed the transmission under the block was in the order of 15–20% for 6 MV and 30% for 18 MV. The MUs calculated for a real patient using the block were about 80% less than the corresponding MUs for the same plan using the multileaf collimator to define the GRID. Based on this investigation, this brass GRID compensator is a viable alternative to other solid compensators or MLC‐based fields currently in use. Its ease of creation and use give it decided advantages. Its ability to be created once and used for multiple patients (by varying the collimation of the linear accelerator jaws) makes it attractive from a cost perspective. We believe this compensator can be put to clinical use, and will allow more centers to offer GRID therapy to their patients. PACS number: 87.53.Mr John Wiley and Sons Inc. 2010-04-26 /pmc/articles/PMC5720442/ /pubmed/20717082 http://dx.doi.org/10.1120/jacmp.v11i3.3163 Text en © 2010 The Authors. This is an open access article under the terms of the Creative Commons Attribution (http://creativecommons.org/licenses/by/3.0/) License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.
spellingShingle Radiation Oncology Physics
Buckey, Courtney
Stathakis, Sotirios
Cashon, Ken
Gutierrez, Alonso
Esquivel, Carlos
Shi, Chengyu
Papanikolaou, Nikos
Evaluation of a commercially‐available block for spatially fractionated radiation therapy
title Evaluation of a commercially‐available block for spatially fractionated radiation therapy
title_full Evaluation of a commercially‐available block for spatially fractionated radiation therapy
title_fullStr Evaluation of a commercially‐available block for spatially fractionated radiation therapy
title_full_unstemmed Evaluation of a commercially‐available block for spatially fractionated radiation therapy
title_short Evaluation of a commercially‐available block for spatially fractionated radiation therapy
title_sort evaluation of a commercially‐available block for spatially fractionated radiation therapy
topic Radiation Oncology Physics
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5720442/
https://www.ncbi.nlm.nih.gov/pubmed/20717082
http://dx.doi.org/10.1120/jacmp.v11i3.3163
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