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Cytoprotective effect exerted by geraniin in HepG2 cells is through microRNA mediated regulation of BACH-1 and HO-1

Geraniin, a hydrolysable tannin, used in traditional medicine in Southeast Asia, is known to exhibit various biological activities. As an antioxidant it is known to up-regulate phase II enzyme Heme oxygenase-1 (HO-1). However its mechanism is not clearly understood. Nuclear factor erythroid-derived...

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Detalles Bibliográficos
Autores principales: Aayadi, Hoda, Mittal, Smriti P.K., Deshpande, Anjali, Gore, Makarand, Ghaskadbi, Saroj S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Korean Society for Biochemistry and Molecular Biology 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5720469/
https://www.ncbi.nlm.nih.gov/pubmed/28602161
http://dx.doi.org/10.5483/BMBRep.2017.50.11.060