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Investigation into the use of a MOSFET dosimeter as an implantable fiducial marker

It may be possible to use a single device to measure the in vivo dose delivered during radiotherapy, as well as to localize the target volume. This potential, as well as the detectors' ability to relate dosimetry and localization, were evaluated using two implantable MOSFET dosimeters placed in...

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Autores principales: Kry, Stephen F, Price, Michael, Wang, Zhonglu, Mourtada, Firas, Salehpour, Mohammad
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5720503/
https://www.ncbi.nlm.nih.gov/pubmed/19223838
http://dx.doi.org/10.1120/jacmp.v10i1.2893
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author Kry, Stephen F
Price, Michael
Wang, Zhonglu
Mourtada, Firas
Salehpour, Mohammad
author_facet Kry, Stephen F
Price, Michael
Wang, Zhonglu
Mourtada, Firas
Salehpour, Mohammad
author_sort Kry, Stephen F
collection PubMed
description It may be possible to use a single device to measure the in vivo dose delivered during radiotherapy, as well as to localize the target volume. This potential, as well as the detectors' ability to relate dosimetry and localization, were evaluated using two implantable MOSFET dosimeters placed inside an acrylic pelvic phantom. A wedged‐field photon plan and an eight‐field prostate treatment plan were developed. For each plan, conditions were simulated so that detectors were in their correct positions or slightly displaced to represent patient setup error and/or organ motion. Doses measured by the two detectors after irradiation were compared to those calculated by the treatment planning software. Additionally, using localization software and kilovoltage images of each setup, the displacement of the detectors from their correct locations was calculated and compared to the induced physical displacement. For all alignments and detector positions, measured and calculated doses showed an average disagreement of 2.7%. The detectors were easily visualized radiographically and the induced detector displacements were typically recognized by the localization software to within 0.1 cm. The implantable detector functioned well as both an internal dosimeter and as an internal fiducial marker, and thus may be useful as a clinical tool to localize the target volume and verify dose delivery in vivo. PACS numbers: 87.53.‐j 87.55.‐x
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spelling pubmed-57205032018-04-02 Investigation into the use of a MOSFET dosimeter as an implantable fiducial marker Kry, Stephen F Price, Michael Wang, Zhonglu Mourtada, Firas Salehpour, Mohammad J Appl Clin Med Phys Radiation Oncology Physics It may be possible to use a single device to measure the in vivo dose delivered during radiotherapy, as well as to localize the target volume. This potential, as well as the detectors' ability to relate dosimetry and localization, were evaluated using two implantable MOSFET dosimeters placed inside an acrylic pelvic phantom. A wedged‐field photon plan and an eight‐field prostate treatment plan were developed. For each plan, conditions were simulated so that detectors were in their correct positions or slightly displaced to represent patient setup error and/or organ motion. Doses measured by the two detectors after irradiation were compared to those calculated by the treatment planning software. Additionally, using localization software and kilovoltage images of each setup, the displacement of the detectors from their correct locations was calculated and compared to the induced physical displacement. For all alignments and detector positions, measured and calculated doses showed an average disagreement of 2.7%. The detectors were easily visualized radiographically and the induced detector displacements were typically recognized by the localization software to within 0.1 cm. The implantable detector functioned well as both an internal dosimeter and as an internal fiducial marker, and thus may be useful as a clinical tool to localize the target volume and verify dose delivery in vivo. PACS numbers: 87.53.‐j 87.55.‐x John Wiley and Sons Inc. 2009-01-27 /pmc/articles/PMC5720503/ /pubmed/19223838 http://dx.doi.org/10.1120/jacmp.v10i1.2893 Text en © 2009 The Authors. This is an open access article under the terms of the Creative Commons Attribution (http://creativecommons.org/licenses/by/3.0/) License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.
spellingShingle Radiation Oncology Physics
Kry, Stephen F
Price, Michael
Wang, Zhonglu
Mourtada, Firas
Salehpour, Mohammad
Investigation into the use of a MOSFET dosimeter as an implantable fiducial marker
title Investigation into the use of a MOSFET dosimeter as an implantable fiducial marker
title_full Investigation into the use of a MOSFET dosimeter as an implantable fiducial marker
title_fullStr Investigation into the use of a MOSFET dosimeter as an implantable fiducial marker
title_full_unstemmed Investigation into the use of a MOSFET dosimeter as an implantable fiducial marker
title_short Investigation into the use of a MOSFET dosimeter as an implantable fiducial marker
title_sort investigation into the use of a mosfet dosimeter as an implantable fiducial marker
topic Radiation Oncology Physics
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5720503/
https://www.ncbi.nlm.nih.gov/pubmed/19223838
http://dx.doi.org/10.1120/jacmp.v10i1.2893
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