Cargando…

ISN Forefronts Symposium 2015: The Diverse Function of Macrophages in Renal Disease

Experimental and human studies indicate that macrophages play a key role within the diseased kidney and represent a target for novel therapies. This brief review outlines the involvement and nature of macrophages in renal disease and highlights the phenotypic plasticity of these cells and their resp...

Descripción completa

Detalles Bibliográficos
Autores principales: Duthie, Fiona, O’Sullivan, Eoin D., Hughes, Jeremy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5720538/
http://dx.doi.org/10.1016/j.ekir.2016.08.004
Descripción
Sumario:Experimental and human studies indicate that macrophages play a key role within the diseased kidney and represent a target for novel therapies. This brief review outlines the involvement and nature of macrophages in renal disease and highlights the phenotypic plasticity of these cells and their responsiveness to the renal microenvironment.