Triptolide Promotes Senescence of Prostate Cancer Cells Through Histone Methylation and Heterochromatin Formation

BACKGROUND: Triptolide is a medicinal herb-derived diterpene triepoxide with potent anti-tumor activity, mainly, correlated with its ability to inhibit and inactivate subunits of RNA polymerase II, thereby suppressing global gene transcription. Epigenetic imbalance including histone methylation are...

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Detalles Bibliográficos
Autores principales: Tamgue, Ousman, Lei, Ming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: West Asia Organization for Cancer Prevention 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5720660/
https://www.ncbi.nlm.nih.gov/pubmed/28952292
http://dx.doi.org/10.22034/APJCP.2017.18.9.2519

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5720660/
https://www.ncbi.nlm.nih.gov/pubmed/28952292
http://dx.doi.org/10.22034/APJCP.2017.18.9.2519

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