Cargando…

OCT4 expression mediates partial cardiomyocyte reprogramming of mesenchymal stromal cells

Mesenchymal stem/stromal cells (MSCs) are in numerous cell therapy clinical trials, including for injured myocardium. Acquisition of cardiomyocyte characteristics by MSCs may improve cardiac regeneration but the mechanisms regulating this process are unclear. Here, we investigated whether the plurip...

Descripción completa

Detalles Bibliográficos
Autores principales:	Yannarelli, Gustavo, Pacienza, Natalia, Montanari, Sonia, Santa-Cruz, Diego, Viswanathan, Sowmya, Keating, Armand
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2017
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5720736/ https://www.ncbi.nlm.nih.gov/pubmed/29216265 http://dx.doi.org/10.1371/journal.pone.0189131

Ejemplares similares

OCT4 Silencing Triggers Its Epigenetic Repression and Impairs the Osteogenic and Adipogenic Differentiation of Mesenchymal Stromal Cells
por: Malvicini, Ricardo, et al.
Publicado: (2019)

Mesenchymal Stem Cell Therapy Facilitates Donor Lung Preservation by Reducing Oxidative Damage during Ischemia
por: Pacienza, Natalia, et al.
Publicado: (2019)

Heme oxygenase up-regulation under ultraviolet-B radiation is not epigenetically restricted and involves specific stress-related transcriptions factors
por: Santa-Cruz, Diego, et al.
Publicado: (2017)

Ion exchange chromatography as a simple and scalable method to isolate biologically active small extracellular vesicles from conditioned media
por: Malvicini, Ricardo, et al.
Publicado: (2023)

CD9: A possible clue into breast cancer chemoresistance
por: Pacienza, Natalia, et al.
Publicado: (2019)

In Vitro Macrophage Assay Predicts the In Vivo Anti-inflammatory Potential of Exosomes from Human Mesenchymal Stromal Cells
por: Pacienza, Natalia, et al.
Publicado: (2018)

Partial Reprogramming of Pluripotent Stem Cell-Derived Cardiomyocytes into Neurons
por: Chuang, Wenpo, et al.
Publicado: (2017)

Mesenchymal Stromal Cell-Derived Extracellular Vesicles as Biological Carriers for Drug Delivery in Cancer Therapy
por: Sanmartin, María Cecilia, et al.
Publicado: (2022)

Concise Review: Wharton's Jelly: The Rich, but Enigmatic, Source of Mesenchymal Stromal Cells
por: Davies, John E., et al.
Publicado: (2017)

Chromatographic Scalable Method to Isolate Engineered Extracellular Vesicles Derived from Mesenchymal Stem Cells for the Treatment of Liver Fibrosis in Mice
por: Domínguez, Luciana M., et al.
Publicado: (2023)

Collagen scaffold enhances the regenerative properties of mesenchymal stromal cells
por: Rashedi, Iran, et al.
Publicado: (2017)

Culture-expanded mesenchymal stromal cell therapy: does it work in knee osteoarthritis? A pathway to clinical success
por: Copp, Griffin, et al.
Publicado: (2023)

A Systematic Study of the Effect of Different Molecular Weights of Hyaluronic Acid on Mesenchymal Stromal Cell-Mediated Immunomodulation
por: Gómez-Aristizábal, Alejandro, et al.
Publicado: (2016)

Direct reprogramming of fibroblasts into cardiomyocytes
por: Chen, Yueqiu, et al.
Publicado: (2017)

Senescent mesenchymal stem/stromal cells in pre-metastatic bone marrow of untreated advanced breast cancer patients
por: BORZONE, FRANCISCO RAÚL, et al.
Publicado: (2023)

miRNA-mediated control of exogenous OCT4 during mesenchymal-epithelial transition increases measles vector reprogramming efficiency
por: Rallabandi, Ramya, et al.
Publicado: (2021)

Bone Marrow Mesenchymal Stromal Cell Treatment in Patients with Osteoarthritis Results in Overall Improvement in Pain and Symptoms and Reduces Synovial Inflammation
por: Chahal, Jaskarndip, et al.
Publicado: (2019)

RNA-Based Strategies for Cardiac Reprogramming of Human Mesenchymal Stromal Cells
por: Mueller, Paula, et al.
Publicado: (2020)

Putative critical quality attribute matrix identifies mesenchymal stromal cells with potent immunomodulatory and angiogenic “fitness” ranges in response to culture process parameters
por: Robb, Kevin P., et al.
Publicado: (2022)

Counteracting Activities of OCT4 and KLF4 during Reprogramming to Pluripotency
por: Tiemann, Ulf, et al.
Publicado: (2014)

The MEK/ERK Module Is Reprogrammed in Remodeling Adult Cardiomyocytes
por: Thomas, Kubin, et al.
Publicado: (2020)

Reprogramming competence of OCT factors is determined by transactivation domains
por: Kim, Kee-Pyo, et al.
Publicado: (2020)

Biological importance of OCT transcription factors in reprogramming and development
por: Kim, Kee-Pyo, et al.
Publicado: (2021)

Heme Oxygenase Contributes to Alleviate Salinity Damage in Glycine max L. Leaves
por: Zilli, Carla Giannina, et al.
Publicado: (2009)

Enhancement of soybean nodulation by seed treatment with non–thermal plasmas
por: Pérez-Pizá, María Cecilia, et al.
Publicado: (2020)

Developmental Reprogramming in Mesenchymal Stromal Cells of Human Subjects with Idiopathic Pulmonary Fibrosis
por: Chanda, Diptiman, et al.
Publicado: (2016)

Mesenchymal Stromal Cell Bioreactor for Ex Vivo Reprogramming of Human Immune Cells
por: Allen, Ashley, et al.
Publicado: (2020)

Age reprogramming: cell rejuvenation by partial reprogramming
por: Singh, Prim B., et al.
Publicado: (2022)

The Potentiality of Human Umbilical Cord Isolated Mesenchymal Stem/Stromal Cells for Cardiomyocyte Generation
por: Abou-ElNaga, Amoura, et al.
Publicado: (2020)

The Role of Isocitrate Dehydrogenases in Direct Reprogramming to Cardiomyocytes
por: Ishida, Tomoaki, et al.
Publicado: (2021)

Cardiomyocyte Ploidy, Metabolic Reprogramming and Heart Repair
por: Elia, Andrea, et al.
Publicado: (2023)

Enhanced OCT4 transcriptional activity substitutes for exogenous SOX2 in cellular reprogramming
por: Marthaler, Adele G., et al.
Publicado: (2016)

Phenotype instability of hepatocyte-like cells produced by direct reprogramming of mesenchymal stromal cells
por: Orge, Iasmim Diniz, et al.
Publicado: (2020)

Human-stimulated oocyte extract induces genetic and mitochondrial reprogramming of mesenchymal stromal cells
por: El-Gammal, Zaynab, et al.
Publicado: (2020)

The CIt protocol: A blueprint to potentiate the immunogenicity of immunoproteasome-reprogrammed mesenchymal stromal cells
por: Bikorimana, Jean-Pierre, et al.
Publicado: (2022)

Mesenchymal Stromal Cells Facilitate Neutrophil-Trained Immunity by Reprogramming Hematopoietic Stem Cells
por: Ng, Julie, et al.
Publicado: (2023)

Banking Mesenchymal Stromal Cells from Umbilical Cord Tissue: Large Sample Size Analysis Reveals Consistency Between Donors
por: Raileanu, Vanessa N., et al.
Publicado: (2019)

The Potentiality of Human Umbilical Cord Isolated Mesenchymal Stem/Stromal Cells for Cardiomyocyte Generation [Corrigendum]
Publicado: (2021)

Exogenous OCT4 and SOX2 Contribution to In Vitro Reprogramming in Cattle
por: Machado, Lucas Simões, et al.
Publicado: (2023)

In vivo reprogramming of murine cardiac fibroblasts into induced cardiomyocytes
por: Qian, Li, et al.
Publicado: (2012)

Cannot write session to /tmp/vufind_sessions/sess_kc1jkpe20hrqgnj2jn1lbhot9b