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Transcription factors, coregulators, and epigenetic marks are linearly correlated and highly redundant
The DNA microstates that regulate transcription include sequence-specific transcription factors (TFs), coregulatory complexes, nucleosomes, histone modifications, DNA methylation, and parts of the three-dimensional architecture of genomes, which could create an enormous combinatorial complexity acro...
Autores principales: | Ahsendorf, Tobias, Müller, Franz-Josef, Topkar, Ved, Gunawardena, Jeremy, Eils, Roland |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5720766/ https://www.ncbi.nlm.nih.gov/pubmed/29216191 http://dx.doi.org/10.1371/journal.pone.0186324 |
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