Recombinant Vaccinia virus-coded interferon inhibitor B18R: Expression, refolding and a use in a mammalian expression system with a RNA-vector

B18R protein of Vaccinia virus binds to type I interferons and inhibits activation of interferon-mediated signal transduction. Cells which have unimpaired interferon signaling such as primary cell cultures or some industrially important cell lines are capable of development of an antiviral state. An...

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Detalles Bibliográficos
Autores principales: Kim, Yuriy G., Baltabekova, Aliya Zh., Zhiyenbay, Erzhan E., Aksambayeva, Altynai S., Shagyrova, Zhadyra S., Khannanov, Rinat, Ramanculov, Erlan M., Shustov, Alexandr V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5720773/
https://www.ncbi.nlm.nih.gov/pubmed/29216299
http://dx.doi.org/10.1371/journal.pone.0189308

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