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Horizontal acquisition of a hypoxia-responsive molybdenum cofactor biosynthesis pathway contributed to Mycobacterium tuberculosis pathoadaptation

The unique ability of the tuberculosis (TB) bacillus, Mycobacterium tuberculosis, to persist for long periods of time in lung hypoxic lesions chiefly contributes to the global burden of latent TB. We and others previously reported that the M. tuberculosis ancestor underwent massive episodes of horiz...

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Detalles Bibliográficos
Autores principales: Levillain, Florence, Poquet, Yannick, Mallet, Ludovic, Mazères, Serge, Marceau, Michael, Brosch, Roland, Bange, Franz-Christoph, Supply, Philip, Magalon, Axel, Neyrolles, Olivier
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5720804/
https://www.ncbi.nlm.nih.gov/pubmed/29176894
http://dx.doi.org/10.1371/journal.ppat.1006752