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Horizontal acquisition of a hypoxia-responsive molybdenum cofactor biosynthesis pathway contributed to Mycobacterium tuberculosis pathoadaptation
The unique ability of the tuberculosis (TB) bacillus, Mycobacterium tuberculosis, to persist for long periods of time in lung hypoxic lesions chiefly contributes to the global burden of latent TB. We and others previously reported that the M. tuberculosis ancestor underwent massive episodes of horiz...
Autores principales: | Levillain, Florence, Poquet, Yannick, Mallet, Ludovic, Mazères, Serge, Marceau, Michael, Brosch, Roland, Bange, Franz-Christoph, Supply, Philip, Magalon, Axel, Neyrolles, Olivier |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5720804/ https://www.ncbi.nlm.nih.gov/pubmed/29176894 http://dx.doi.org/10.1371/journal.ppat.1006752 |
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