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Merkel cell polyomavirus small T antigen induces genome instability by E3 ubiquitin ligase targeting
The formation of a bipolar mitotic spindle is an essential process for the equal segregation of duplicated DNA into two daughter cells during mitosis. As a result of deregulated cellular signaling pathways, cancer cells often suffer a loss of genome integrity that might etiologically contribute to c...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group
2017
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5720911/ https://www.ncbi.nlm.nih.gov/pubmed/28846109 http://dx.doi.org/10.1038/onc.2017.277 |