(68)Ga-PSMA PET-CT Imaging of Metastatic Adenoid Cystic Carcinoma

A patient with a history of adenoid cystic carcinoma of the nasal cavity presented himself with bone pain and an elevated PSA level. On suspicion of metastatic prostate cancer a (68)Ga-PSMA PET-CT was performed. The PET-CT showed numerous lung and non-sclerotic bone metastasis. Biopsy of a bone meta...

Descripción completa

Detalles Bibliográficos
Autores principales: de Keizer, Bart, Krijger, Gerard C., Ververs, F. Tessa, van Es, Robert J. J., de Bree, Remco, Willems, Stefan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2016
Materias:
Interesting Image
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5721081/
https://www.ncbi.nlm.nih.gov/pubmed/29242733
http://dx.doi.org/10.1007/s13139-016-0445-6
_version_ 1783284756926955520
author de Keizer, Bart
Krijger, Gerard C.
Ververs, F. Tessa
van Es, Robert J. J.
de Bree, Remco
Willems, Stefan
author_facet de Keizer, Bart
Krijger, Gerard C.
Ververs, F. Tessa
van Es, Robert J. J.
de Bree, Remco
Willems, Stefan
author_sort de Keizer, Bart
collection PubMed
description A patient with a history of adenoid cystic carcinoma of the nasal cavity presented himself with bone pain and an elevated PSA level. On suspicion of metastatic prostate cancer a (68)Ga-PSMA PET-CT was performed. The PET-CT showed numerous lung and non-sclerotic bone metastasis. Biopsy of a bone metastasis was performed and pathology showed adenoid cystic carcinoma instead of prostate cancer. Immunohistochemical PSMA staining of the primary tumour showed intense PSMA expression in adenoid cystic carcinoma tumour cells. Because of the high PSMA expression of adenoid cystic carcinoma, (68)Ga-PSMA PET-CT might be a promising imaging modality for this malignancy.
format Online
Article
Text
id pubmed-5721081
institution National Center for Biotechnology Information
language English
publishDate 2016
publisher Springer Berlin Heidelberg
record_format MEDLINE/PubMed
spelling pubmed-57210812017-12-14 (68)Ga-PSMA PET-CT Imaging of Metastatic Adenoid Cystic Carcinoma de Keizer, Bart Krijger, Gerard C. Ververs, F. Tessa van Es, Robert J. J. de Bree, Remco Willems, Stefan Nucl Med Mol Imaging Interesting Image A patient with a history of adenoid cystic carcinoma of the nasal cavity presented himself with bone pain and an elevated PSA level. On suspicion of metastatic prostate cancer a (68)Ga-PSMA PET-CT was performed. The PET-CT showed numerous lung and non-sclerotic bone metastasis. Biopsy of a bone metastasis was performed and pathology showed adenoid cystic carcinoma instead of prostate cancer. Immunohistochemical PSMA staining of the primary tumour showed intense PSMA expression in adenoid cystic carcinoma tumour cells. Because of the high PSMA expression of adenoid cystic carcinoma, (68)Ga-PSMA PET-CT might be a promising imaging modality for this malignancy. Springer Berlin Heidelberg 2016-08-16 2017-12 /pmc/articles/PMC5721081/ /pubmed/29242733 http://dx.doi.org/10.1007/s13139-016-0445-6 Text en © The Author(s) 2016 Open Access This article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made.
spellingShingle Interesting Image
de Keizer, Bart
Krijger, Gerard C.
Ververs, F. Tessa
van Es, Robert J. J.
de Bree, Remco
Willems, Stefan
(68)Ga-PSMA PET-CT Imaging of Metastatic Adenoid Cystic Carcinoma
title (68)Ga-PSMA PET-CT Imaging of Metastatic Adenoid Cystic Carcinoma
title_full (68)Ga-PSMA PET-CT Imaging of Metastatic Adenoid Cystic Carcinoma
title_fullStr (68)Ga-PSMA PET-CT Imaging of Metastatic Adenoid Cystic Carcinoma
title_full_unstemmed (68)Ga-PSMA PET-CT Imaging of Metastatic Adenoid Cystic Carcinoma
title_short (68)Ga-PSMA PET-CT Imaging of Metastatic Adenoid Cystic Carcinoma
title_sort (68)ga-psma pet-ct imaging of metastatic adenoid cystic carcinoma
topic Interesting Image
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5721081/
https://www.ncbi.nlm.nih.gov/pubmed/29242733
http://dx.doi.org/10.1007/s13139-016-0445-6
work_keys_str_mv AT dekeizerbart 68gapsmapetctimagingofmetastaticadenoidcysticcarcinoma
AT krijgergerardc 68gapsmapetctimagingofmetastaticadenoidcysticcarcinoma
AT verversftessa 68gapsmapetctimagingofmetastaticadenoidcysticcarcinoma
AT vanesrobertjj 68gapsmapetctimagingofmetastaticadenoidcysticcarcinoma
AT debreeremco 68gapsmapetctimagingofmetastaticadenoidcysticcarcinoma
AT willemsstefan 68gapsmapetctimagingofmetastaticadenoidcysticcarcinoma

Ejemplares similares