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A Robust System for Production of Superabundant VP1 Recombinant AAV Vectors
Recombinant adeno-associated viral (rAAV) vectors have been widely used in human gene therapy. One major impediment to its broad application is the inability to produce high-quality vectors in mass quantity. Here, an efficient and scalable suspension cell culture system for the production of rAAV ve...
Autores principales: | Wang, Qizhao, Wu, Zhongren, Zhang, Junping, Firrman, Jenni, Wei, Hongying, Zhuang, Zhengjing, Liu, LinShu, Miao, Linqing, Hu, Yang, Li, Dong, Diao, Yong, Xiao, Weidong |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society of Gene & Cell Therapy
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5721209/ https://www.ncbi.nlm.nih.gov/pubmed/29255740 http://dx.doi.org/10.1016/j.omtm.2017.11.002 |
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