The role of human cytochrome P450 2E1 in liver inflammation and fibrosis

Cytochrome P450 2E1 (CYP2E1) plays an important role in alcohol and toxin metabolism by catalyzing the conversion of substrates into more polar metabolites and producing reactive oxygen species. Reactive oxygen species‐induced oxidative stress promotes hepatocyte injury and death, which in turn indu...

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Detalles Bibliográficos
Autores principales: Xu, Jun, Ma, Hsiao‐Yen, Liang, Shuang, Sun, Mengxi, Karin, Gabriel, Koyama, Yukinori, Hu, Ronglin, Quehenberger, Oswald, Davidson, Nicholas O., Dennis, Edward A., Kisseleva, Tatiana, Brenner, David A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5721400/
https://www.ncbi.nlm.nih.gov/pubmed/29404441
http://dx.doi.org/10.1002/hep4.1115

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