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Hairy and enhancer of split 6 prevents hepatic lipid accumulation through inhibition of Pparg2 expression

Peroxisome proliferator‐activated receptor gamma (PPARγ) is a master regulator for white adipocyte differentiation and lipid storage. The increased level of hepatic PPARγ2 isoform reprograms liver for lipid storage and causes abnormal fat accumulation in certain pathophysiologic conditions. The curr...

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Detalles Bibliográficos
Autores principales: Park, Jung Eun, Lee, Mikang, Kim, Seong‐Chul, Zhang, Yanqiao, Hardwick, James P., Lee, Yoon Kwang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5721401/
https://www.ncbi.nlm.nih.gov/pubmed/29404444
http://dx.doi.org/10.1002/hep4.1120