Cargando…

Generation of safe and therapeutically effective human induced pluripotent stem cell‐derived hepatocyte‐like cells for regenerative medicine

Hepatocyte‐like cells (HLCs) differentiated from human induced pluripotent stem (iPS) cells are expected to be applied for regenerative medicine. In this study, we attempted to generate safe and therapeutically effective human iPS‐HLCs for hepatocyte transplantation. First, human iPS‐HLCs were gener...

Descripción completa

Detalles Bibliográficos
Autores principales:	Takayama, Kazuo, Akita, Naoki, Mimura, Natsumi, Akahira, Rina, Taniguchi, Yukimasa, Ikeda, Makoto, Sakurai, Fuminori, Ohara, Osamu, Morio, Tomohiro, Sekiguchi, Kiyotoshi, Mizuguchi, Hiroyuki
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2017
Materias:	Original Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5721405/ https://www.ncbi.nlm.nih.gov/pubmed/29404442 http://dx.doi.org/10.1002/hep4.1111

Ejemplares similares

Comparison of commercially available media for hepatic differentiation and hepatocyte maintenance
por: Toba, Yukiko, et al.
Publicado: (2020)

Human induced-pluripotent stem cell-derived hepatocyte-like cells as an in vitro model of human hepatitis B virus infection
por: Sakurai, Fuminori, et al.
Publicado: (2017)

Laminin fragments conjugated with perlecan’s growth factor-binding domain differentiate human induced pluripotent stem cells into skin-derived precursor cells
por: Sugiyama-Nakagiri, Yoriko, et al.
Publicado: (2023)

Direct conversion of human fibroblasts into hepatocyte-like cells by ATF5, PROX1, FOXA2, FOXA3, and HNF4A transduction
por: Nakamori, Daiki, et al.
Publicado: (2017)

Generation of a bile salt export pump deficiency model using patient-specific induced pluripotent stem cell-derived hepatocyte-like cells
por: Imagawa, Kazuo, et al.
Publicado: (2017)

Long-Term Self-Renewal of Human ES/iPS-Derived Hepatoblast-like Cells on Human Laminin 111-Coated Dishes
por: Takayama, Kazuo, et al.
Publicado: (2013)

Generation of enterocyte-like cells from human induced pluripotent stem cells for drug absorption and metabolism studies in human small intestine
por: Ozawa, Tatsuya, et al.
Publicado: (2015)

Laminin E8 fragments support efficient adhesion and expansion of dissociated human pluripotent stem cells
por: Miyazaki, Takamichi, et al.
Publicado: (2012)

Erratum: Laminin E8 fragments support efficient adhesion and expansion of dissociated human pluripotent stem cells
por: Miyazaki, Takamichi, et al.
Publicado: (2013)

HHEX Promotes Hepatic-Lineage Specification through the Negative Regulation of Eomesodermin
por: Watanabe, Hitoshi, et al.
Publicado: (2014)

Human iPS Cell–based Liver-like Tissue Engineering at Extrahepatic Sites in Mice as a New Cell Therapy for Hemophilia B
por: Okamoto, Ryota, et al.
Publicado: (2018)

Prediction of Differentiation Tendency Toward Hepatocytes from Gene Expression in Undifferentiated Human Pluripotent Stem Cells
por: Yanagihara, Kana, et al.
Publicado: (2016)

Laminin-guided highly efficient endothelial commitment from human pluripotent stem cells
por: Ohta, Ryo, et al.
Publicado: (2016)

Mechanistic basis for the recognition of laminin-511 by α6β1 integrin
por: Takizawa, Mamoru, et al.
Publicado: (2017)

miR-27b antagonizes BMP signaling in early differentiation of human induced pluripotent stem cells
por: Lim, Jaeeun, et al.
Publicado: (2021)

FGF signal is not required for hepatoblast differentiation of human iPS cells
por: Toba, Yukiko, et al.
Publicado: (2019)

Efficient Generation of Small Intestinal Epithelial-like Cells from Human iPSCs for Drug Absorption and Metabolism Studies
por: Negoro, Ryosuke, et al.
Publicado: (2018)

A novel efficient feeder-free culture system for the derivation of human induced pluripotent stem cells
por: Nakagawa, Masato, et al.
Publicado: (2014)

Highly efficient biallelic genome editing of human ES/iPS cells using a CRISPR/Cas9 or TALEN system
por: Takayama, Kazuo, et al.
Publicado: (2017)

Laminin γ1 C-terminal Glu to Gln mutation induces early postimplantation lethality
por: Kiyozumi, Daiji, et al.
Publicado: (2018)

Structural mechanism of laminin recognition by integrin
por: Arimori, Takao, et al.
Publicado: (2021)

Pretreatment with Perlecan-Conjugated Laminin-E8 Fragment Enhances Maturation of Grafted Dopaminergic Progenitors in Parkinson’s Disease Model
por: Adachi, Hiromasa, et al.
Publicado: (2022)

Efficient antitumor effects of a novel oncolytic adenovirus fully composed of species B adenovirus serotype 35
por: Ono, Ryosuke, et al.
Publicado: (2021)

Adenovirus vector-mediated macrophage erythroblast attacher (MAEA) overexpression in primary mouse hepatocytes attenuates hepatic gluconeogenesis
por: Shimizu, Kahori, et al.
Publicado: (2017)

miR-27b-mediated suppression of aquaporin-11 expression in hepatocytes reduces HCV genomic RNA levels but not viral titers
por: Sakurai, Fuminori, et al.
Publicado: (2019)

In Vitro Model for a Drug Assessment of Cytochrome P450 Family 3 Subfamily A Member 4 Substrates Using Human Induced Pluripotent Stem Cells and Genome Editing Technology
por: Deguchi, Sayaka, et al.
Publicado: (2021)

Molecular profiling of the basement membrane of pluripotent epiblast cells in post-implantation stage mouse embryos
por: Futaki, Sugiko, et al.
Publicado: (2019)

Decellularized Organ-Derived Scaffold Is a Promising Carrier for Human Induced Pluripotent Stem Cells-Derived Hepatocytes
por: Kojima, Hideaki, et al.
Publicado: (2022)

Expedited approval system for regenerative medicine products – Is it unusual?
por: Yano, Kazuo, et al.
Publicado: (2016)

Neonatal Gene Therapy for Hemophilia B by a Novel Adenovirus Vector Showing Reduced Leaky Expression of Viral Genes
por: Iizuka, Shunsuke, et al.
Publicado: (2017)

Type I Interferons Impede Short Hairpin RNA-Mediated RNAi via Inhibition of Dicer-Mediated Processing to Small Interfering RNA
por: Machitani, Mitsuhiro, et al.
Publicado: (2017)

Efficient and Directive Generation of Two Distinct Endoderm Lineages from Human ESCs and iPSCs by Differentiation Stage-Specific SOX17 Transduction
por: Takayama, Kazuo, et al.
Publicado: (2011)

Visualization of basement membranes by a nidogen-based fluorescent reporter in mice
por: Futaki, Sugiko, et al.
Publicado: (2023)

Regulators of pluripotency and their implications in regenerative medicine
por: El-Badawy, Ahmed, et al.
Publicado: (2015)

Establishment of SLC15A1/PEPT1-Knockout Human-Induced Pluripotent Stem Cell Line for Intestinal Drug Absorption Studies
por: Kawai, Kanae, et al.
Publicado: (2019)

Pluripotent stem cell-based therapies and their path to the clinic
por: Takayama, Kazuo, et al.
Publicado: (2023)

Systemically Administered Reovirus-Induced Downregulation of Hypoxia Inducible Factor-1α in Subcutaneous Tumors
por: Hotani, Takuma, et al.
Publicado: (2018)

Adenovirus vector-based vaccine for infectious diseases
por: Sakurai, Fuminori, et al.
Publicado: (2022)

Generation of Brain Microvascular Endothelial-Like Cells from Human Induced Pluripotent Stem Cells by Co-Culture with C6 Glioma Cells
por: Minami, Haruka, et al.
Publicado: (2015)

Cell-Type-Specific Adhesiveness and Proliferation Propensity on Laminin Isoforms Enable Purification of iPSC-Derived Corneal Epithelium
por: Shibata, Shun, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_i99m8ng0md059dh7qt4g1jusfs