Engineered FGF19 eliminates bile acid toxicity and lipotoxicity leading to resolution of steatohepatitis and fibrosis in mice

Nonalcoholic fatty liver disease (NAFLD) is an increasingly prevalent chronic liver disease for which no approved therapies are available. Despite intensive research, the cellular mechanisms that mediate NAFLD pathogenesis and progression are poorly understood. Although obesity, diabetes, insulin re...

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Detalles Bibliográficos
Autores principales: Zhou, Mei, Learned, R. Marc, Rossi, Stephen J., DePaoli, Alex M., Tian, Hui, Ling, Lei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5721409/
https://www.ncbi.nlm.nih.gov/pubmed/29404440
http://dx.doi.org/10.1002/hep4.1108

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5721409/
https://www.ncbi.nlm.nih.gov/pubmed/29404440
http://dx.doi.org/10.1002/hep4.1108

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