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Sequencing of hepatitis C virus for detection of resistance to direct‐acting antiviral therapy: A systematic review

The significance of the clinical impact of direct‐acting antiviral (DAA) resistance‐associated substitutions (RASs) in hepatitis C virus (HCV) on treatment failure is unclear. No standardized methods or guidelines for detection of DAA RASs in HCV exist. To facilitate further evaluations of the impac...

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Detalles Bibliográficos
Autores principales: Bartlett, Sofia R., Grebely, Jason, Eltahla, Auda A., Reeves, Jacqueline D., Howe, Anita Y.M., Miller, Veronica, Ceccherini‐Silberstein, Francesca, Bull, Rowena A., Douglas, Mark W., Dore, Gregory J., Harrington, Patrick, Lloyd, Andrew R., Jacka, Brendan, Matthews, Gail V., Wang, Gary P., Pawlotsky, Jean‐Michel, Feld, Jordan J., Schinkel, Janke, Garcia, Federico, Lennerstrand, Johan, Applegate, Tanya L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5721421/
https://www.ncbi.nlm.nih.gov/pubmed/29404466
http://dx.doi.org/10.1002/hep4.1050