Up‐regulation of golgi α‐mannosidase IA and down‐regulation of golgi α‐mannosidase IC activates unfolded protein response during hepatocarcinogenesis

α‐1,2 mannosidases, key enzymes in N‐glycosylation, are required for the formation of mature glycoproteins in eukaryotes. Aberrant regulation of α‐1,2 mannosidases can result in cancer, although the underlying mechanisms are unclear. Here, we report the distinct roles of α‐1,2 mannosidase subtypes (...

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Detalles Bibliográficos
Autores principales: Tu, Hsiao‐Chen, Hsiao, Yung‐Chun, Yang, Wan‐Yu, Tsai, Shin‐Lin, Lin, Hua‐Kuo, Liao, Chong‐Yi, Lu, Jeng‐Wei, Chou, Yu‐Ting, Wang, Horng‐Dar, Yuh, Chiou‐Hwa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5721452/
https://www.ncbi.nlm.nih.gov/pubmed/29404456
http://dx.doi.org/10.1002/hep4.1032

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5721452/
https://www.ncbi.nlm.nih.gov/pubmed/29404456
http://dx.doi.org/10.1002/hep4.1032

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