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Treating fatty liver disease by modulating mitochondrial pyruvate metabolism

Modifying the entry of pyruvate into mitochondria may provide a unique approach to treat metabolic disease. The pharmacology of a new class of insulin sensitizers directed against a newly identified mitochondrial target may treat many aspects of nonalcoholic steatohepatitis, including fibrosis. This...

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Detalles Bibliográficos
Autores principales:	Colca, Jerry R., McDonald, William G., McCommis, Kyle S., Finck, Brian N.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2017
Materias:	Brief Report
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5721453/ https://www.ncbi.nlm.nih.gov/pubmed/29404453 http://dx.doi.org/10.1002/hep4.1036

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