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The ectonucleotidase ENTPD1/CD39 limits biliary injury and fibrosis in mouse models of sclerosing cholangitis

The pathogenesis of primary sclerosing cholangitis (PSC) and the mechanistic link to inflammatory bowel disease remain ill‐defined. Ectonucleoside triphosphate diphosphohydrolase‐1 (ENTPD1)/clusters of differentiation (CD) 39, the dominant purinergic ecto‐enzyme, modulates intestinal inflammation. H...

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Detalles Bibliográficos
Autores principales: Peng, Zhen‐Wei, Rothweiler, Sonja, Wei, Guangyan, Ikenaga, Naoki, Liu, Susan B., Sverdlov, Deanna Y., Vaid, Kahini A., Longhi, Maria Serena, Kuang, Ming, Robson, Simon C., Popov, Yury V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5721459/
https://www.ncbi.nlm.nih.gov/pubmed/29404503
http://dx.doi.org/10.1002/hep4.1084

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