Treatment with a DNA methyltransferase inhibitor feminizes zebrafish and induces long-term expression changes in the gonads

BACKGROUND: The role of epigenetic modifications such as DNA methylation during vertebrate sexual development is far from being clear. Using the zebrafish model, we tested the effects of one of the most common DNA methyltransferase (dnmt) inhibitor, 5-aza-2′-deoxycytidine (5-aza-dC), which is approv...

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Detalles Bibliográficos
Autores principales: Ribas, Laia, Vanezis, Konstantinos, Imués, Marco Antonio, Piferrer, Francesc
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5721477/
https://www.ncbi.nlm.nih.gov/pubmed/29216900
http://dx.doi.org/10.1186/s13072-017-0168-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5721477/
https://www.ncbi.nlm.nih.gov/pubmed/29216900
http://dx.doi.org/10.1186/s13072-017-0168-7

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