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Low serum ferritin and G6PD deficiency as potential predictors of anaemia in pregnant women visiting Prime Care Hospital Enugu Nigeria

OBJECTIVES: Though iron deficiency is known to be a major risk factor of anaemia, the association of G6PD deficiency and malaria with anaemia still remains unclear. Hence, a cross-sectional study involving 95 pregnant women visiting Prime Care Hospital in Trans-Ekulu region of Enugu Nigeria was cond...

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Autores principales: Engwa, Godwill Azeh, Unaegbu, Marcellus, Unachukwu, Marian N., Njoku, Mary-Gloria C., Agbafor, Kingsley N., Mbacham, Wilfred Fon, Okoh, Anthony
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5721478/
https://www.ncbi.nlm.nih.gov/pubmed/29221497
http://dx.doi.org/10.1186/s13104-017-3051-5
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author Engwa, Godwill Azeh
Unaegbu, Marcellus
Unachukwu, Marian N.
Njoku, Mary-Gloria C.
Agbafor, Kingsley N.
Mbacham, Wilfred Fon
Okoh, Anthony
author_facet Engwa, Godwill Azeh
Unaegbu, Marcellus
Unachukwu, Marian N.
Njoku, Mary-Gloria C.
Agbafor, Kingsley N.
Mbacham, Wilfred Fon
Okoh, Anthony
author_sort Engwa, Godwill Azeh
collection PubMed
description OBJECTIVES: Though iron deficiency is known to be a major risk factor of anaemia, the association of G6PD deficiency and malaria with anaemia still remains unclear. Hence, a cross-sectional study involving 95 pregnant women visiting Prime Care Hospital in Trans-Ekulu region of Enugu Nigeria was conducted to determine possible predictors of anaemia in pregnancy. RESULTS: The prevalence of anaemia, malaria and G6PD deficiency were 53.7, 12.6 and 60% respectively. Low serum ferritin (OR 5.500, CI 2.25–13.42, p < 0.05) and G6PD deficiency (OR 0.087, CI 0.03–0.23, p < 0.05) were associated with anaemia in pregnancy. On the other hand, malaria did not significantly associate (OR 1.184, CI 0.35–3.97, p = 0.964) with anaemia in pregnant women. These findings showed high prevalence of anaemia among pregnant women with low serum ferritin level and G6PD deficiency as high risk factors of anaemia.
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spelling pubmed-57214782017-12-11 Low serum ferritin and G6PD deficiency as potential predictors of anaemia in pregnant women visiting Prime Care Hospital Enugu Nigeria Engwa, Godwill Azeh Unaegbu, Marcellus Unachukwu, Marian N. Njoku, Mary-Gloria C. Agbafor, Kingsley N. Mbacham, Wilfred Fon Okoh, Anthony BMC Res Notes Research Note OBJECTIVES: Though iron deficiency is known to be a major risk factor of anaemia, the association of G6PD deficiency and malaria with anaemia still remains unclear. Hence, a cross-sectional study involving 95 pregnant women visiting Prime Care Hospital in Trans-Ekulu region of Enugu Nigeria was conducted to determine possible predictors of anaemia in pregnancy. RESULTS: The prevalence of anaemia, malaria and G6PD deficiency were 53.7, 12.6 and 60% respectively. Low serum ferritin (OR 5.500, CI 2.25–13.42, p < 0.05) and G6PD deficiency (OR 0.087, CI 0.03–0.23, p < 0.05) were associated with anaemia in pregnancy. On the other hand, malaria did not significantly associate (OR 1.184, CI 0.35–3.97, p = 0.964) with anaemia in pregnant women. These findings showed high prevalence of anaemia among pregnant women with low serum ferritin level and G6PD deficiency as high risk factors of anaemia. BioMed Central 2017-12-08 /pmc/articles/PMC5721478/ /pubmed/29221497 http://dx.doi.org/10.1186/s13104-017-3051-5 Text en © The Author(s) 2017 Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.
spellingShingle Research Note
Engwa, Godwill Azeh
Unaegbu, Marcellus
Unachukwu, Marian N.
Njoku, Mary-Gloria C.
Agbafor, Kingsley N.
Mbacham, Wilfred Fon
Okoh, Anthony
Low serum ferritin and G6PD deficiency as potential predictors of anaemia in pregnant women visiting Prime Care Hospital Enugu Nigeria
title Low serum ferritin and G6PD deficiency as potential predictors of anaemia in pregnant women visiting Prime Care Hospital Enugu Nigeria
title_full Low serum ferritin and G6PD deficiency as potential predictors of anaemia in pregnant women visiting Prime Care Hospital Enugu Nigeria
title_fullStr Low serum ferritin and G6PD deficiency as potential predictors of anaemia in pregnant women visiting Prime Care Hospital Enugu Nigeria
title_full_unstemmed Low serum ferritin and G6PD deficiency as potential predictors of anaemia in pregnant women visiting Prime Care Hospital Enugu Nigeria
title_short Low serum ferritin and G6PD deficiency as potential predictors of anaemia in pregnant women visiting Prime Care Hospital Enugu Nigeria
title_sort low serum ferritin and g6pd deficiency as potential predictors of anaemia in pregnant women visiting prime care hospital enugu nigeria
topic Research Note
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5721478/
https://www.ncbi.nlm.nih.gov/pubmed/29221497
http://dx.doi.org/10.1186/s13104-017-3051-5
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