Study of the uncertainty in the determination of the absorbed dose to water during external beam radiotherapy calibration

To achieve a good clinical outcome in radiotherapy treatment, a certain accuracy in the dose delivered to the patient is required. Therefore, it is necessary to keep the uncertainty in each of the steps of the process inside some acceptable values, which implies as low a global uncertainty as possible. The work reported here focused on the uncertainty evaluation of absorbed dose to water in the routine calibration for clinical beams in the range of energies used in external‐beam radiotherapy. With this aim, we considered various uncertainty components (corrected electrometer reading, calibration factor, beam quality correction factor, and reference conditions) associated with beam calibration. Results show a typical uncertainty in the determination of absorbed dose to water during beam calibration of approximately 1.3% for photon beams and 1.5% for electron beams ([Formula: see text] in both cases) when the [Formula: see text] formalism is used and [Formula: see text] is calculated theoretically. These values may vary depending on the uncertainty provided by the standards laboratory for calibration factor, which is shown in the work. For primary standards based on clinical linear accelerator beam energies, the uncertainty in this step of the process could be placed close to 1.0%. We also discuss the possibility of an uncertainty reduction with the adoption of the absorbed dose to water formalism as compared with the air kerma formalism. PACS numbers: 87.53.Dq, 87.53.Hv