Telomere heterogeneity linked to metabolism and pluripotency state revealed by simultaneous analysis of telomere length and RNA-seq in the same human embryonic stem cell

BACKGROUND: Telomere length heterogeneity has been detected in various cell types, including stem cells and cancer cells. Cell heterogeneity in pluripotent stem cells, such as embryonic stem cells (ESCs), is of particular interest; however, the implication and mechanisms underlying the heterogeneity...

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Detalles Bibliográficos
Autores principales: Wang, Hua, Zhang, Kunshan, Liu, Yifei, Fu, Yudong, Gao, Shan, Gong, Peng, Wang, Haiying, Zhou, Zhongcheng, Zeng, Ming, Wu, Zhenfeng, Sun, Yu, Chen, Tong, Li, Siguang, Liu, Lin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5721592/
https://www.ncbi.nlm.nih.gov/pubmed/29216888
http://dx.doi.org/10.1186/s12915-017-0453-8

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