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Adaptive phenotype drives resistance to androgen deprivation therapy in prostate cancer

BACKGROUND: Prostate cancer (PCa), the second most common cancer affecting men worldwide, shows a broad spectrum of biological and clinical behaviour representing the epiphenomenon of an extreme heterogeneity. Androgen deprivation therapy is the mainstay of treatment for advanced forms but after few...

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Detalles Bibliográficos
Autores principales: Ferrari, Nicoletta, Granata, Ilaria, Capaia, Matteo, Piccirillo, Marina, Guarracino, Mario Rosario, Venè, Roberta, Brizzolara, Antonella, Petretto, Andrea, Inglese, Elvira, Morini, Martina, Astigiano, Simonetta, Amaro, Adriana Agnese, Boccardo, Francesco, Balbi, Cecilia, Barboro, Paola
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5721601/
https://www.ncbi.nlm.nih.gov/pubmed/29216878
http://dx.doi.org/10.1186/s12964-017-0206-x