Targeting the cross-talk between Urokinase receptor and Formyl peptide receptor type 1 to prevent invasion and trans-endothelial migration of melanoma cells

BACKGROUND: Accumulating evidence demonstrates that the Urokinase Receptor (uPAR) regulates tumor cell migration through its assembly in composite regulatory units with transmembrane receptors, and uPAR(88–92) is the minimal sequence required to induce cell motility through the Formyl Peptide Recept...

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Detalles Bibliográficos
Autores principales: Ragone, Concetta, Minopoli, Michele, Ingangi, Vincenzo, Botti, Giovanni, Fratangelo, Federica, Pessi, Antonello, Stoppelli, Maria Patrizia, Ascierto, Paolo Antonio, Ciliberto, Gennaro, Motti, Maria Letizia, Carriero, Maria Vincenza
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5721612/
https://www.ncbi.nlm.nih.gov/pubmed/29216889
http://dx.doi.org/10.1186/s13046-017-0650-x

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