Intracerebroventricular delivery of hematopoietic progenitors results in rapid and robust engraftment of microglia-like cells

Recent evidence indicates that hematopoietic stem and progenitor cells (HSPCs) can serve as vehicles for therapeutic molecular delivery to the brain by contributing to the turnover of resident myeloid cell populations. However, such engraftment needs to be fast and efficient to exert its therapeutic...

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Detalles Bibliográficos
Autores principales: Capotondo, Alessia, Milazzo, Rita, Garcia-Manteiga, Jose M., Cavalca, Eleonora, Montepeloso, Annita, Garrison, Brian S., Peviani, Marco, Rossi, Derrick J., Biffi, Alessandra
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2017
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5721728/
https://www.ncbi.nlm.nih.gov/pubmed/29226242
http://dx.doi.org/10.1126/sciadv.1701211

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