Inhibition of Vascular c‐Jun N‐Terminal Kinase 2 Improves Obesity‐Induced Endothelial Dysfunction After Roux‐en‐Y Gastric Bypass

BACKGROUND: Roux‐en‐Y gastric bypass (RYGB) reduces obesity‐associated comorbidities and cardiovascular mortality. RYGB improves endothelial dysfunction, reducing c‐Jun N‐terminal kinase (JNK) vascular phosphorylation. JNK activation links obesity with insulin resistance and endothelial dysfunction....

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Detalles Bibliográficos
Autores principales: Doytcheva, Petia, Bächler, Thomas, Tarasco, Erika, Marzolla, Vincenzo, Engeli, Michael, Pellegrini, Giovanni, Stivala, Simona, Rohrer, Lucia, Tona, Francesco, Camici, Giovanni G., Vanhoutte, Paul M., Matter, Christian M., Lutz, Thomas A., Lüscher, Thomas F., Osto, Elena
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5721746/
https://www.ncbi.nlm.nih.gov/pubmed/29138180
http://dx.doi.org/10.1161/JAHA.117.006441

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